Author

A. W. Middleton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lindqvist· 2 shared E. Mullers· 1 shared H. Silva Cascales· 1 shared H. Stoy· 1 shared K. Akopyan· 1 shared K. Burdova· 1 shared L. Baranello· 1 shared L. Macurek· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. Lindqvist

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate Plk1

H. Silva Cascales, K. Burdova, A. W. Middleton, V. Kuzin, E. Mullers, H. Stoy, L. Baranello, L. Macurek, A. Lindqvist

This study shows Cyclin A2 localizes to the cytoplasm at the S/G2 transition to activate PLK1 by interacting with Bora, and this cytoplasmic presence is restricted by p21.

bioRxiv · Jul 29, 2020Cell Biology

p53-dependent polyploidisation after DNA damage in G2 phase

A. W. Middleton, R. Suman, P. O'Toole, K. Akopyan, A. Lindqvist

This study shows that G2 phase cell cycle exit in p53-positive cells can lead to polyploidisation through repeated DNA re-replication rather than senescence.

bioRxiv · Jun 9, 2020 · PreprintCell Biology