Author

K. Akopyan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

A. Lindqvist· 2 shared A. W. Middleton· 1 shared P. O'Toole· 1 shared R. Suman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersCell Biology

A. Lindqvist

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2 papers

Recent·Most cited

Wee1 inhibition decouples Cdk1 and Plk1 activities: a role for gradual Cdk1 activation throughout G2 phase.

K. Akopyan, A. Lindqvist

This study shows that gradual Cdk1 activation during G2 phase coordinates mitotic factor production and CDK1/PLK1 activation, and that WEE1 inhibition disrupts this coordination.

bioRxiv · Mar 15, 2024 · PreprintCell Biology

p53-dependent polyploidisation after DNA damage in G2 phase

A. W. Middleton, R. Suman, P. O'Toole, K. Akopyan, A. Lindqvist

This study shows that G2 phase cell cycle exit in p53-positive cells can lead to polyploidisation through repeated DNA re-replication rather than senescence.

bioRxiv · Jun 9, 2020 · PreprintCell Biology