Structure-Guided Mutagenesis Targeting Interactions between pp150 Tegument Protein and Small Capsid Protein Identify Five Lethal and Two Live Attenuated HCMV Mutants
A. W. Stevens, R. Cruz-Cosme, N. Armstrong, Q. Tang, Z. H. Zhou
The paper identifies five lethal and two live attenuated HCMV mutants by mutating pp150-capsid interactions, revealing critical residues for viral replication.
bioRxiv · Jan 22, 2024Microbiology