IRG1 and iNOS act redundantly with other interferon gamma induced factors to restrict intracellular replication of Legionella pneumophila.
J. V. Price, D. Russo, D. X. Ji, R. A. Chavez, L. DiPeso, A. Y.-F. Lee, J. Coers, R. Vance
The paper identifies six IFN-gamma-induced genes, including IRG1 and iNOS, that redundantly restrict L. pneumophila replication in macrophages.
bioRxiv · Aug 10, 2019Immunology