Evolution towards extremely high β-lactam resistance in Mycobacterium abscessus outbreak strains
E. le run, T. Herve, S. Holland, A. Zelazny
This study identifies genetic changes in M. abscessus outbreak strains that lead to high imipenem resistance, suggesting carbapenem/{beta}-lactamase inhibitor combinations for treatment.
bioRxiv · May 8, 2024 · PreprintMicrobiology