S. Holland

Co-circulation of distinct high pathogenicity avian influenza virus (HPAIV) subtypes in a mass mortality event in wild seabirds and co-location with dead seals

The paper reports the co-circulation of H5N1 and H5N5 HPAIV subtypes in a mass mortality event involving seabirds and seals in Great Britain, with the first recorded instance of two subtypes co-occurring in the same avian population and the first H5N5 detection in mammals in GB.

Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy

This study demonstrates that peptide amphiphile nanostructures enhance cancer imaging and therapy by hitchhiking on endogenous biomolecules to target tumors effectively.

Synergistic Effects of Sulopenem in Combination with Cefuroxime or Durlobactam against Mycobacterium abscessus

This study shows that sulopenem combined with cefuroxime or durlobactam synergistically inhibits Mycobacterium abscessus, with BLIs enhancing antibacterial effects.

An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV

This paper introduces an ACE2 decamer viral trap that neutralizes multiple SARS-CoV-2 variants and related coronaviruses through inhalation, showing durability and effectiveness in preclinical models.

Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19

The paper uses genetically diverse mice to model varied innate immune responses to SARS-CoV-2 infection, showing differences in survival, viral replication, and cytokine profiles.