Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants
A.-B. Blanc-Potard, P. Garai, L. Berry, M. Moussouni, S. Bleves
This study reveals that Pseudomonas aeruginosa uses the type III secretion system (T3SS) and ExoS effector to escape macrophage phagosomes and induce cell lysis, with MgtC and OprF modulating T3SS expression.
bioRxiv · Aug 10, 2018Microbiology