L. Berry

Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model

This study shows that Pseudomonas aeruginosa persists intracellularly in zebrafish wounds, evading antibiotics and host immunity, and can be re-sensitized by anti-biofilm agents.

HCF101 is a novel component of the CIA cytosolic iron-sulfur synthesis pathway in the human pathogen Toxoplasma gondii

This paper identifies HCF101 as a novel component of the cytosolic Fe-S assembly pathway in Toxoplasma gondii, essential for parasite survival and a potential drug target.

Iron depletion has different consequences on the growth and survival of Toxoplasma gondii strains

This study examines how iron depletion affects different Toxoplasma gondii strains, finding that acute strains are more sensitive than cystogenic strains.

Disrupting the plastid-hosted iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability

This study shows that disrupting the SUF iron-sulfur cluster pathway in Toxoplasma gondii severely impairs parasite growth and viability through multiple metabolic and functional defects.

Druggable redox pathways against M. abscessus in cystic fibrosis patient-derived airway organoids

This study uses airway organoids to investigate M. abscessus infection in CF patients, showing antioxidant pathways can inhibit bacterial growth and enhance antibiotic efficacy.

The genome of stress tolerant crop wild relativePaspalum vaginatum leads to increased biomassproductivity in the crop Zea mays

This study sequenced Paspalum vaginatum, a stress-tolerant wild relative of maize, and found that inducing trehalose accumulation in maize increases biomass through autophagy.

Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion

The paper shows that pharmacological activation of PIEZO1 in human red blood cells inhibits Plasmodium falciparum invasion without affecting parasite growth.

Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

This study identifies PfPP1 as essential for Plasmodium falciparum egress from host erythrocytes and shows it integrates internal and external signals for this process.

Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling

This study shows that apicomplexan parasites adapt to host nutritional changes by shifting lipid acquisition between de novo synthesis and host scavenging, involving apicoplast lipid metabolism and host organelle remodeling.

Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants

This study reveals that Pseudomonas aeruginosa uses the type III secretion system (T3SS) and ExoS effector to escape macrophage phagosomes and induce cell lysis, with MgtC and OprF modulating T3SS expression.

Common Piezo1 allele in African populations causes xerocytosis and attenuates Plasmodium infection

The paper identifies a common Piezo1 variant in African populations that causes xerocytosis and reduces Plasmodium infection.