Genome-wide CRISPR Screens Identify Ferroptosis as a Novel Therapeutic Vulnerability in Acute Lymphoblastic Leukemia
M.-E. Lalonde, M. Sasseville, A.-M. Gelinas, J.-S. Milanese, K. Beland, S. Drouin, E. Haddad, R. Marcotte
This study identifies ferroptosis as a therapeutic vulnerability in B-ALL through genome-wide CRISPR screens and validates it in patient-derived samples.
bioRxiv · Feb 1, 2022Cancer Biology