RUNX1 controls the dynamics of cell cycle entry of naive resting B cells by regulating expression of cell cycle and immunomodulatory genes in response to BCR stimulation
I. Thomsen, N. Kunowska, R. de Souza, A.-M. Moody, G. Crawford, Y.-F. Wang, S. Khadayate, J. Strid, M. M. Karimi, A. Barr, N. Dillon, P. Sabbattini
This study shows RUNX1 regulates B cell cycle entry and immunomodulatory gene expression in response to BCR stimulation, linking it to autoimmunity.
bioRxiv · Dec 1, 2020Immunology