Author

Y.-F. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2

Frequent Co-Authors

H.-Z. Li· 4 shared Y.-L. Liu· 4 shared Z.-G. Xu· 4 shared Z.-Y. Guo· 4 shared X.-X. Shao· 2 shared A. Barr· 1 shared A. E. X. Brown· 1 shared A. G. Fisher· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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4 shared papersBiochemistry

H.-Z. Li

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

The ghrelin receptor GHSR has two efficient agonists in an ancient fish species

H.-Z. Li, Y.-F. Wang, Y.-S. Zheng, Y.-L. Liu, Z.-G. Xu, Z.-Y. Guo

The study identifies that GHSR in coelacanth binds and is activated by motilin, while zebrafish and large yellow croaker GHSRs do not bind motilin, suggesting ancient fish GHSRs had two agonists.

bioRxiv · Jun 3, 2023 · PreprintBiochemistry

Nanomolar range of FAM237B can activate receptor GPR83

H.-Z. Li, Y.-F. Wang, W.-F. Hu, Y.-L. Liu, Z.-G. Xu, Z.-Y. Guo

The paper shows that FAM237B activates GPR83 at nanomolar concentrations, confirming it as an endogenous agonist.

bioRxiv · May 4, 2023Biochemistry

FAM237A, rather than peptide PEN and proCCK56-63, is a ligand of the orphan receptor GPR83

H.-Z. Li, Y.-F. Wang, X.-X. Shao, Y.-L. Liu, Z.-G. Xu, S.-L. Wang, Z.-Y. Guo

This study identifies FAM237A as the true ligand of GPR83, refuting previous claims that PEN and proCCK56-63 are agonists of this receptor.

bioRxiv · Sep 27, 2022 · PreprintBiochemistry

LEAP2 is a more conserved ligand than ghrelin for fish GHSRs

H.-Z. Li, X.-X. Shao, Y.-F. Wang, Y.-L. Liu, Z.-G. Xu, Z.-Y. Guo

The paper shows LEAP2 binds more consistently to fish GHSRs than ghrelin, suggesting LEAP2 is a more conserved ligand in these species.

bioRxiv · Sep 21, 2022Biochemistry

RUNX1 controls the dynamics of cell cycle entry of naive resting B cells by regulating expression of cell cycle and immunomodulatory genes in response to BCR stimulation

I. Thomsen, N. Kunowska, R. de Souza, A.-M. Moody, G. Crawford, Y.-F. Wang, S. Khadayate, J. Strid, M. M. Karimi, A. Barr, N. Dillon, P. Sabbattini

This study shows RUNX1 regulates B cell cycle entry and immunomodulatory gene expression in response to BCR stimulation, linking it to autoimmunity.

bioRxiv · Dec 1, 2020Immunology

Partial rescue of neuronal genes deregulated in Cornelia de Lange Syndrome by cohesin

F. D. Weiss, L. Calderon, Y.-F. Wang, R. Georgieva, Y. Guo, N. Cvetesic, M. Kaur, G. Dharmalingam, I. D. Krantz, B. Lenhard, A. G. Fisher, M. Merkenschlager

The paper investigates cohesin's role in neuronal gene expression in CdLS by analyzing transcriptomes and showing partial rescue of gene deregulation through cohesin reconstitution.

bioRxiv · Jun 6, 2020Cell Biology

Systemic muscle wasting and coordinated tumour response drive tumourigenesis

H. Newton, Y.-F. Wang, L. Camplese, A. E. X. Brown, S. Hirabayashi

The paper identifies a systemic nutrient circuit in Drosophila that links muscle wasting with tumour growth via proline scavenging, and shows similar patterns in human kidney cancer.

bioRxiv · Sep 27, 2019Cancer Biology