The genetic architecture of gene expression in individuals of African and European ancestry
Kipper Fletez‐Brant, Renan Sauteraud, Yanyu Liang, Steven J. Micheletti, Priyanka Nandakumar, Aarathi Sugathan, Kijoung S Song, Taylor B. Cavazos, Aimee L. Thomas, Robert J. Tunney, Barry Hicks, Jared O’Connell, Suyash Shringarpure, Katelyn Kukar, Meghan E. Moreno, , Vladimir Vacic
This study compares eQTL discovery in African and European ancestry cohorts, finding more eQTLs in African samples and improved GWAS variant-to-gene mapping using African eQTLs.
medRxiv · Dec 13, 2024 · PreprintGenetic & Genomic Medicine