This study finds that higher polygenic risk scores for breast cancer are associated with longer survival in patients, suggesting a link between genetic predisposition and less aggressive tumors.

BMC Cancer · Aug 28, 2025Peer-reviewedGenetic & Genomic Medicine

Multivariate genome-wide association analysis of quantitative reading skill and dyslexia improves gene discovery

Hayley S. Mountford, Else Eising, Pierre Fontanillas, Adam Auton, Stella W. Aslibekyan, Robert K. Bell, Katelyn Kukar Bond, Zayn Cochinwala, Sayantan Das, Kahsaia de Brito, Emily DelloRusso, Chris Q. Eijsbouts, Sarah L. Elson, Chris German, Julie M. Granka, , Michelle Luciano A

This study uses a multivariate GWAS approach to identify genetic loci associated with reading ability and dyslexia, finding 35 new genome-wide significant loci and estimating SNP heritability at 24%.

Translational Psychiatry · Aug 18, 2025Peer-reviewedGenetic & Genomic Medicine

The genetic architecture of gene expression in individuals of African and European ancestry

Kipper Fletez‐Brant, Renan Sauteraud, Yanyu Liang, Steven J. Micheletti, Priyanka Nandakumar, Aarathi Sugathan, Kijoung S Song, Taylor B. Cavazos, Aimee L. Thomas, Robert J. Tunney, Barry Hicks, Jared O’Connell, Suyash Shringarpure, Katelyn Kukar, Meghan E. Moreno, , Vladimir Vacic

This study compares eQTL discovery in African and European ancestry cohorts, finding more eQTLs in African samples and improved GWAS variant-to-gene mapping using African eQTLs.

medRxiv · Dec 13, 2024 · PreprintGenetic & Genomic Medicine

Bidirectional relationship between olfaction and Parkinson's disease

Jonggeol Jeffrey Kim, Sara Bandrés‐Ciga, Karl Heilbron, Stella W. Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg, Jonathan Bowes, Katarzyna Bryc, Ninad S. Chaudhary, Daniella Coker, Sayantan Das, Emily DelloRusso, Sarah L. Elson, , Alastair John Noyce

This study identifies genetic correlations between hyposmia and Parkinson's disease, finding a strong causal link from PD to hyposmia but weaker evidence for the reverse.

npj Parkinson s Disease · Dec 5, 2024Peer-reviewedGenetic & Genomic Medicine

The shared genetic architecture and evolution of human language and musical rhythm

Gökberk Alagöz, Else Eising, Yasmina Mekki, Giacomo Bignardi, Pierre Fontanillas, Stella W. Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg, Jonathan Bowes, Katarzyna Bryc, Ninad S. Chaudhary, Daniella Coker, Sayantan Das, , Reyna L. Gordon

This study investigates the shared genetic architecture between rhythm and dyslexia using large-scale genome-wide association studies.

Nature Human Behaviour · Nov 21, 2024Peer-reviewedGenomics