Renan Sauteraud

Gateway: patient olfactory neurons for large-scale discovery in neurodegenerative disease

The paper introduces Gateway, a platform for collecting and analyzing single-cell transcriptomic data from patient olfactory neurons to study neurodegenerative diseases.

IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

This study identifies B cell-intrinsic and -extrinsic mechanisms by which IRF7 promotes spontaneous autoimmune germinal center and plasma cell responses, autoantibody production, and SLE development.

The genetic architecture of gene expression in individuals of African and European ancestry

This study compares eQTL discovery in African and European ancestry cohorts, finding more eQTLs in African samples and improved GWAS variant-to-gene mapping using African eQTLs.