Overcoming steric inhibition of antibody-dependent phagocytosiswith tall adhesions
Aymeric Chorlay, Aaron M. Joffe, Jared Huzar, Jaffar Hasnain, Caitlin E. Cornell, Phillip L. Geissler, Daniel A. Fletcher
This paper shows that tall adhesion proteins can overcome steric inhibition of phagocytosis by promoting close contact between macrophages and target cells in crowded environments.
Nature Communications · Sep 28, 2026Peer-reviewedBiophysics