TFEB activation ameliorates listeriolysin O-mediated subversion of lysosomal and LC3 function during Listeria monocytogenes infection
Aarti Pant, Sneha Bhatt, Parul Sen, Deepam Bhattacharya, Kuldeep Singh Rautela, Mamta Negi, Ravi R. Manjithaya
This study identifies LLO's role in subverting xenophagy by binding LC3 and inhibiting TFEB, and shows that restoring these functions reduces Listeria monocytogenes infection.
bioRxiv · Nov 30, 2025 · PreprintCell Biology