Ravi R. Manjithaya

This study shows that α-synuclein protofibrils induce tunneling nanotubes in astrocytes, promoting stemness and apoptosis resistance through pFAK-Nanog interaction and p53 degradation.

This study investigates the role of ADA2 in yeast, showing it regulates triterpene metabolism, phospholipid homeostasis, and autophagy through interactions with TORC1 and the Pah1 pathway.

This paper develops a dual-reporter HTS assay to identify HIV-1 latency-modulating agents, finding 27 candidate LPAs and LRA compounds from a chemical library.

This study identifies LLO's role in subverting xenophagy by binding LC3 and inhibiting TFEB, and shows that restoring these functions reduces Listeria monocytogenes infection.

This study shows Atg11, an autophagy-related protein, regulates microtubule dynamics and chromosome segregation in yeast by affecting spindle pole body function and Kar9-dependent spindle positioning.

This study shows that PC4 maintains genomic integrity by regulating chromatin structure and autophagy, with its loss increasing radiation resistance through autophagy enhancement.

This study identifies gene expression patterns in testicular germ cells from azoospermia patients and links disruptions to spermatogenic arrest and male infertility.