Contrasting contribution of embryo- and postnatally-derived brain-resident macrophages in sustaining sleep-wake circuitry
Ali Seifinejad, Mojtaba Bandarabadi, Meriem Haddar, Saskia Wundt, Mehdi Tafti, Anne Vassalli, Abbas Khani, Gianni Monaco
This study shows that embryonic and postnatally-derived brain macrophages have distinct roles in regulating sleep-wake cycles and synaptic balance, with postnatal repopulation failing to restore normal sleep patterns.
bioRxiv · Jan 22, 2024 · PreprintNeuroscience