Mehdi Tafti

This study investigates the distinct roles of OX1R and OX2R in modulating dopaminergic neuron activity and socio-emotional behaviors in mice, revealing differential impacts on anxiety, hyperactivity, and learning.

This study shows that low-dose Solriamfetol improves memory and attention in wild-type mice by enhancing EEG fast-gamma activity and reducing delta activity.

This study shows that embryonic and postnatally-derived brain macrophages have distinct roles in regulating sleep-wake cycles and synaptic balance, with postnatal repopulation failing to restore normal sleep patterns.

The paper investigates the role of hypocretin neurons in stabilizing sleep by examining their interaction with noradrenergic neurons.

This study investigates the role of orexin receptors in modulating theta oscillations in dopaminergic neurons during wakefulness and REM sleep, finding that OXR2 loss increases theta power and alters coupling with fast-gamma waves.

The paper shows that narcolepsy with cataplexy is caused by epigenetic silencing of hypocretin neurons, not their destruction, using QRFP as a marker and methylation analysis.