WhiB6 is required for the secretion-dependent regulation of ESX-1 substrates in pathogenic mycobacteria.
Abdallah M. Abdallah, E.M. Weerdenburg, Qingtian Guan, R. Ummels, S. Borggreve, S.A. Adroub, Tareq B. Malas, Raeece Naeem, Huoming Zhang, T.D. Otto, W. Bitter, A. Pain
This study shows that WhiB6 regulates ESX-1 substrate secretion in mycobacteria, independent of structural components, through transcriptional control and protein interactions.
bioRxiv · May 2, 2018 · PreprintMicrobiology