Notch1 induces endothelial plasticity to mediate hyaloid vessel involution
Shaymaa Khazaal, Abdoul-Razak Sango, Megne Ariane Vanessa Megne, Silva Sosa Alexa, kawtar zouine, Gaëlle Mawambo, Rony Chidiac, Bora Kiran, Chen Jing, Malika Oubaha
This study identifies Notch1 as a key regulator of hyaloid vessel regression, showing it drives endothelial plasticity and detachment independent of apoptosis.
bioRxiv · Oct 1, 2025 · PreprintCell Biology