Redox-driven control of Yuh1/UCHL3 impacts mitochondrial health via NEDD8/Rub1 pathway
Soha Issa, Yuval Klein, Eden Berda, Shahaf Saad, Dana Harshuk-Shabso, Abhishek Sinha, Yehonatan Sharaabi, Moran Benhar, Elah Pick
The paper investigates how redox changes affect Yuh1/UCHL3 activity, revealing a thiol-based redox switch that modulates NEDD8/Rub1 processing and impacts mitochondrial health.
bioRxiv · May 20, 2024 · PreprintCell Biology