Premyelinating Oligodendrocyte Survival Governs CNS Remyelination
Michael E. Stockton, Maureen Wentling, Yessenia I. Mancha Corchado, Abigail J. Kucera, Stephanie Karas, Tania A. Seabrook, Clara Mutschler, Lindsay A. Osso, Kristen H. Schuster, Gustavo Della Flora Nunes, Anthony R. Chavez, Ethan G. Hughes
This study shows that premyelinating oligodendrocyte survival affects oligodendrocyte production rates, with increased survival promoting regeneration after demyelination and decreased survival contributing to age-related decline.
bioRxiv · Feb 23, 2026 · PreprintNeuroscience