Michael E. Stockton

This study shows microglia drive myelin loss in MS through autoantibodies and BTK signaling, with implications for therapeutic targeting.

This study shows that premyelinating oligodendrocyte survival affects oligodendrocyte production rates, with increased survival promoting regeneration after demyelination and decreased survival contributing to age-related decline.

This study shows that partial oligodendrocyte restoration after demyelination is sufficient to recover visual cortical function in mice.

This study uses three-photon imaging to show that white matter generates more oligodendrocytes than gray matter, but gray matter shows faster growth rates and regenerative deficits after injury.

The paper evaluates tdTomato and mScarlet fluorescent proteins for dual-color three-photon microscopy in the mouse brain, finding high signal-to-background in specific wavelength ranges.

This paper introduces a CRISPR/Cas9 strategy to edit APP and manipulate the amyloid pathway in Alzheimer's disease by reducing β-cleavage and Aβ while increasing α-cleavage.