Author

Abigail M Keith

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Giuseppe DeganuttiiD· 1 shared Juan MarugániD· 1 shared Lee E. EideniD· 1 shared Marc Ferrer· 1 shared Mark J. HendersoniD· 1 shared Noel T SouthalliD· 1 shared Patrick Michael SextoniD· 1 shared Wenjuan Ye· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Giuseppe DeganuttiORCID

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1 paper

Recent·Most cited

Design of peptide-based PAC1 antagonists combining molecular dynamics simulations and a biologically relevant cell-based assay

Wenqin Xu, Abigail M Keith, Wenjuan Ye, Xin Yang Hu, Noel T Southall, Juan Marugán, Marc Ferrer, Mark J. Henderson, Patrick Michael Sexton, Giuseppe Deganutti, Lee E. Eiden

The paper designs peptide-based PAC1 antagonists using molecular dynamics simulations and a cell-based assay, finding that some proposed small molecule antagonists lack activity while confirming the efficacy of PACAP(6-38) and M65.

Biochemical Pharmacology · Sep 3, 2025Peer-reviewedPharmacology & Toxicology