Author

Abigail P. Spangler

University of Delaware

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Aditya M. KunjapuriD· 2 shared Michaela A. JonesiD· 2 shared Shelby R. AndersoniD· 2 shared D’Jana R. Wyllis· 1 shared Madan R. Gopal· 1 shared Roman M. DickeyiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersSynthetic Biology

Aditya M. KunjapurORCID

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2 papers

Recent·Most cited

A One-Pot Biocatalytic Cascade to Access Diverse L-Phenylalanine Derivatives from Aldehydes or Carboxylic Acids

Shelby R. Anderson, Madan R. Gopal, Abigail P. Spangler, Michaela A. Jones, D’Jana R. Wyllis, Aditya M. Kunjapur

This paper describes a one-pot biocatalytic cascade using PLP-dependent enzymes to synthesize diverse L-phenylalanine derivatives from aldehydes and carboxylic acids under mild conditions.

ChemCatChem · Dec 23, 2024Peer-reviewedSynthetic Biology

Combined biosynthesis and site-specific incorporation of phenylalanine derivatives from aryl aldehydes or carboxylic acids in engineered bacteria

Shelby R. Anderson, Abigail P. Spangler, Michaela A. Jones, Roman M. Dickey, Aditya M. Kunjapur

This paper presents a modular bacterial system for biosynthesizing and incorporating phenylalanine derivatives into proteins using achiral building blocks, reducing reliance on complex chemical synthesis.

bioRxiv · Dec 17, 2024 · PreprintSynthetic Biology