Author

Adam Dobias

Masaryk University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2 Approach:deep learning· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

David BednářiD· 2 shared Gaspar PintoiD· 2 shared Ihor ArefieviD· 2 shared Jan ŠtouračiD· 2 shared Jaroslav ŠtěrbaiD· 2 shared Jiřı́ DamborskýiD· 2 shared Joan Planas-IglesiasiD· 2 shared Ondřej SlabýiD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

David BednářORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Analysis of Mutations in Precision Oncology using The Automated, Accurate, and User-Friendly Web Tool PredictONCO

Rayyan Tariq Khan, Petra Pokorná, Jan Štourač, Simeon Borko, Adam Dobias, Joan Planas-Iglesias, Stanislav Mazurenko, Ihor Arefiev, Gaspar Pinto, Veronika Szotkowská, Jaroslav Štěrba, Jiřı́ Damborský, Ondřej Slabý, David Bednář

PredictONCO is a web tool that predicts the impact of mutations in cancer-related proteins using structural and sequence-based features, achieving high accuracy in variant classification.

Computational and Structural Biotechnology Journal · Nov 14, 2024Peer-reviewedBioinformatics

A Computational Workflow for Analysis of Missense Mutations in Precision Oncology

Rayyan Tariq Khan, Petra Pokorná, Jan Štourač, Simeon Borko, Ihor Arefiev, Joan Planas-Iglesias, Adam Dobias, Gaspar Pinto, Veronika Szotkowská, Jaroslav Štěrba, Ondřej Slabý, Jiřı́ Damborský, Stanislav Mazurenko, David Bednář

This paper presents a bioinformatics pipeline for analyzing missense mutations in oncogenic proteins, providing a probability score for functional impact and suggesting potential FDA/EMA-approved drugs.

Journal of Cheminformatics · Jul 29, 2024Peer-reviewedCancer Biology