Chromosomal Mcm2-7 distribution is the primary driver of the genome replication program in species from yeast to humans
Eric J. Foss, Smitha Sripathy, Tonibelle Gatbonton-Schwager, Hyunchang Kwak, Adam H. Thiesen, Uyen Lao, Antonio Bedalov
The paper shows that chromosomal distribution of Mcm2-7 complexes drives replication timing across species, with exceptions like the inactive X-chromosome.
bioRxiv · Apr 26, 2020 · PreprintGenetics