Author

Uyen Lao

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:yeast· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Antonio BedaloviD· 3 shared Eric J. FossiD· 3 shared Brandon R. Lofts· 2 shared Carmina Lichauco· 2 shared Tonibelle N. Gatbonton-SchwageriD· 2 shared Adam H. Thiesen· 1 shared Erin L. Taylor· 1 shared Hyunchang Kwak· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenetics

Antonio BedalovORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy

Carmina Lichauco, Eric J. Foss, Tonibelle N. Gatbonton-Schwager, Nelson F Athow, Brandon R. Lofts, Robin Acob, Erin L. Taylor, James J Marquez, Uyen Lao, Shawna Miles, Antonio Bedalov

This study shows that Sir2 and Fun30 regulate rDNA replication timing by controlling MCM helicase positioning and nucleosome occupancy in yeast.

eLife · Jan 20, 2025Peer-reviewedGenetics

Identification of 1600 replication origins in S. cerevisiae

Eric J. Foss, Carmina Lichauco, Tonibelle N. Gatbonton-Schwager, Sara J. Gonske, Brandon R. Lofts, Uyen Lao, Antonio Bedalov

The paper identifies 1600 replication origins in S. cerevisiae by analyzing Mcm double-hexamer binding sites and shows replication activity at the most abundant sites.

bioRxiv · Apr 11, 2023 · PreprintGenetics

Chromosomal Mcm2-7 distribution is the primary driver of the genome replication program in species from yeast to humans

Eric J. Foss, Smitha Sripathy, Tonibelle Gatbonton-Schwager, Hyunchang Kwak, Adam H. Thiesen, Uyen Lao, Antonio Bedalov

The paper shows that chromosomal distribution of Mcm2-7 complexes drives replication timing across species, with exceptions like the inactive X-chromosome.

bioRxiv · Apr 26, 2020 · PreprintGenetics