The role of secondary structures of peptide polymers on antimicrobial efficacy and antibiotic potentiation
Swagatam Barman, Alimi Abiodun, Md Waliullah Hossain, Adam Parris, Aiswarya Banshidhar Chandrasseril, Ethan A. Older, Jie Li, Alan W. Decho, Chuanbing Tang
This study shows that helical peptide polymers enhance antibiotic efficacy against multidrug-resistant bacteria by 2-256-fold while maintaining low toxicity.
bioRxiv · Nov 19, 2024 · PreprintMicrobiology