Jie Li

This study shows that CB1 receptor activation promotes microbial dysbiosis by stimulating oxygen-dependent expansion of Enterobacteriaceae, leading to exacerbated colitis.

The paper surveys the biosynthetic potential of the human tumor microbiome, identifying novel metabolites and their potential roles in tumor pathology.

This study shows that Alistipes timonensis colonization in Il10-deficient mice delays colitis by altering the host lipidome and delivering anti-inflammatory outer membrane vesicles containing immunomodulatory lipids.

The paper discovers sulfenicin, a novel natural product with a unique acylsulfenic acid functional group, and identifies the enzymes involved in its biosynthesis.

This paper discovers a new class of cancer immunogenic chemotherapeutic leads called aspercyclicins through a high-throughput screening platform and structural elucidation techniques.

This study shows that helical peptide polymers enhance antibiotic efficacy against multidrug-resistant bacteria by 2-256-fold while maintaining low toxicity.