BORC segregates synaptic vesicle and lysosomal proteins through motors UNC-104/KIF1A and UNC-116/KIF5
Amal Mathew, Sohan Seal, Aditee Dandekar, Badal Singh Chauhan, Sruthi Sivadasan, Michael L. Nonet, Sandhya Padmanabhan Koushika
This study identifies BORC's role in segregating synaptic vesicle and lysosomal proteins in neuronal cell bodies through motors UNC-104/KIF1A and UNC-116/KIF5, with LRK-1 and APB-3 regulating this process.
bioRxiv · Dec 31, 2024 · PreprintCell Biology