Michael L. Nonet

This paper introduces two new methods for creating cis-linked driver/reporter pairs in C. elegans using phiC31 recombinase, simplifying genetic analysis.

This study identifies TOCA-1 as a regulator of collateral branching in C. elegans neurons, showing it promotes actin assembly through WASP-1 and Arp2/3 complex activation.

This study identifies BORC's role in segregating synaptic vesicle and lysosomal proteins in neuronal cell bodies through motors UNC-104/KIF1A and UNC-116/KIF5, with LRK-1 and APB-3 regulating this process.

This study identifies parameters affecting bipartite reporter system expression in C. elegans, providing a framework for designing and optimizing transgenes.

This paper describes a method to rapidly generate single copy transgenes in C. elegans using RMCE and drug selection, achieving homozygous transgenes in 3 generations.