High-Throughput Machine Learning-Aided Antibody Discovery for Cell Surface Antigens
Deepash Kothiwal, Aaron W. Kollasch, Murali Anuganti, Nicholas Hollmer, Anita Ghosh, Roushu Zhang, Haiying Li, Steffan B. Paul, Ruitong Li, Yvrick Zagar, Mina Abdollahi, Zach Anderson, Filmawit Belay, Matthew Salotto, Sophia A. Ulmer, , Rob Meijers
The paper develops a synthetic Fab yeast display library integrated with machine learning to discover antibodies against cell surface antigens, yielding hundreds of validated antibodies and a public dataset.
Cell Systems · Jun 23, 2026Peer-reviewedBiophysics