Deepash Kothiwal

A static web database proposes 55 305 construct suggestions for 5328 human secreted and cell-surface proteins, using AlphaFold pLDDT and PAE, with ortholog, paralog and BLAST cross-reactivity context.

DELPHI is an open platform for predicting antibody developability from sequence, achieving high AUC scores and enabling residue-level engineering insights.

The paper develops a synthetic Fab yeast display library integrated with machine learning to discover antibodies against cell surface antigens, yielding hundreds of validated antibodies and a public dataset.

This study shows that cohesin sumoylation is required for subtelomeric gene repression in yeast, independent of its role in sister chromatid cohesion.

This paper evaluates HILIC and ERLIC chromatography for resolving CTD phosphopeptide isoforms, finding ERLIC improves separation of phosphorylated peptides for LC-MS/MS analysis.