Analysis of the DNA-binding domain of the Pseudomonas aeruginosa quorum sensing transcription factor LasR
Zichu Yang, Anvita Billa, Aditya S Desai, Matthew R. Parsek, Ajai A. Dandekar
The paper investigates mutations in the DNA-binding domain of LasR, a LuxR homolog in Pseudomonas aeruginosa, finding some variants enhance regulation of RhlR-target genes but confer fitness defects.
bioRxiv · Aug 12, 2026 · PreprintMicrobiology