PBF/PTTG1IP coordinates focal adhesion formation, polarity and cell motility
Merve Kocbiyik, Selvambigai Manivannan, Davina Banga, Aditi Hariharan, Mohammed E. El‐Asrag, Andrew David Beggs, Paloma García, Dean P. Larner, Saroop Raja, Jeremy Andrew Pike, Afshan Afzal, Katie Brookes, Hannah R. Nieto, Steven G. Thomas, Martin L. Read, , Vicki E. Smith
This study identifies PBF/PTTG1IP as an endogenous regulator of cell adhesion, polarity, and directional motility by analyzing knockout models and phosphoproteomic data.
bioRxiv · Sep 16, 2026 · PreprintCell Biology