Jeremy Andrew Pike

This study identifies PBF/PTTG1IP as an endogenous regulator of cell adhesion, polarity, and directional motility by analyzing knockout models and phosphoproteomic data.

Nano-org provides a curated resource of single-molecule localisation microscopy data for studying protein nanoscale distributions and their relationships across cell types and conditions.

This study uses a magnetic particle-based platform to mechanically modulate T-cell receptors, showing that NFAT pathway signaling accumulation is required for CD4+ T cell activation.

This study uses expansion microscopy to quantitatively analyze the structure of platelet aggregates under normal and perturbed conditions.

The paper shows that male sex hormones and reduced plakoglobin impair atrial conduction and sodium currents in mice, contributing to atrial remodelling.

This study demonstrates isotropic expansion of the nucleus using expansion microscopy to investigate nanoscale DNA damage response structures.

FrenchFISH improves DNA copy number quantification from FISH images by using Poisson models, outperforming manual and automated methods in ovarian cancer tissue sections.

This paper presents an analysis workflow for quantifying platelet spreading and morphology using image segmentation and machine learning, with tools available in KNIME and ilastik.

The paper introduces a topological data analysis method for analyzing single molecule localization microscopy data, improving segmentation and quantifying nano-structure.

This study optimizes CRISPR-Cas9 for single molecule imaging by improving mEos variants and shows endogenous labeling enables accurate quantification of CXCR4.