Novel nanopore sequencing method for determining Human Papillomavirus integrations in tumors without the need for whole genome sequencing
Preetiparna Parida, Nivedita Mukherjee, Agastya Singh, Shirley Christabel Lewis, Krishna Sharan, Sandeep P. Mallya, Ashima Singh, Mahadev Rao, Daniel S. Higginson, Radhakrishnan Sabarinathan, Rama Rao Damerla
The paper develops a nanopore sequencing method to identify HPV integrations in tumors without whole genome sequencing, validated in cell lines and cervical cancer patients.
bioRxiv · Oct 17, 2024 · PreprintGenomics