Nivedita Mukherjee

This study identifies hepatobiliary progenitor-like reprogramming in liver metastases, driven by TGF-β and hypoxia, and shows its association with poor survival.

The paper analyzes two-hit inactivation frequencies in tumor suppressor genes across 9,000 tumors, identifying factors like mutation impact, zygosity, and chromosomal context that influence these frequencies.

The paper develops a nanopore sequencing method to identify HPV integrations in tumors without whole genome sequencing, validated in cell lines and cervical cancer patients.