Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species
Alistair P. Green, Florian Klimm, Aidan S. Marshall, Rein Leetmaa, Juvid Aryaman, Aurora Gómez-Durán, Patrick Francis Chinnery, Nick S. Jones
The paper identifies cryptic mitochondrial DNA mutations in single cells across species and tissues, showing their association with ageing and pathophysiological processes.
bioRxiv · Jul 4, 2023 · PreprintBioinformatics