β-hydroxybutyrate modulates enteric pathogen susceptibility through regulation of commensal bacteria and intestinal Th17 responses
Wenxuan Dong, Chi Yan, Bethany R. Korwin-Mihavics, Kate Stack, Gillian Hughes, Aidan Schmidt, Kevin J. Schwartz, Gustavo G. Caballero-Flores, Margaret Alexander
This study shows that β-hydroxybutyrate (BHB) reduces Th17 cells and SFB abundance, increasing susceptibility to enteric infection by altering gut microbiota.
mSystems · Jul 16, 2026Peer-reviewedMicrobiology