BRG1 defines a genomic subset of inflammatory genes transcriptionally controlled by the glucocorticoid receptor
Aikaterini Mechtidou, Franziska Greulich, Benjamin A. Strickland, Céline Jouffe, Filippo M. Cernilogar, Gunnar Schotta, N. Henriette Uhlenhaut
The paper identifies BRG1 as a key component of a co-repressor complex that GR uses to repress inflammatory genes in macrophages, revealing a non-classical role for the SWI/SNF complex.
bioRxiv · Dec 13, 2021 · PreprintGenomics