Author

Aixi Bai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Bin Xiao· 1 shared Chenjie FengiD· 1 shared Feifei Hu· 1 shared Guiting Zhang· 1 shared Hao YeiD· 1 shared Jie WangiD· 1 shared Qiangcheng Zeng· 1 shared Ruochi ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Bin Xiao

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1 paper

Recent·Most cited

Reinforcement learning with evolutionary priors unlocks multi-site enzyme optimization from sparse experimental feedback

Xiaopeng Xu, Hao Ye, Ziqi Gao, Ruochi Zhang, Xinhai Zhou, Guiting Zhang, Tao Guo, Wenjia He, Chenjie Feng, Bin Xiao, Feifei Hu, Qiangcheng Zeng, Aixi Bai, Xiao Zhang, Jie Wang, Xin Gao

AlphaVariant uses reinforcement learning with evolutionary priors to optimize enzyme variants from sparse experimental data, achieving high activity improvements in multiple rounds of optimization.

bioRxiv · Oct 21, 2026 · PreprintBioinformatics