Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation
Yuma Cho, Akari Taniguchi, Akiharu Kubo, Junichi Ikenouchi
This study identifies the Rho-ROCK pathway's role in cleaving EpCAM/TROP2 to release claudin for rapid de novo tight junction formation during epithelial turnover.
eLife · Jul 24, 2025Peer-reviewedCell Biology