Phospholipids that plug the pores of cholesteryl ester transfer protein control its lipid transfer dynamics
Sukriti Sacher, Praveen Singh, Abhishek Mukherjee, Akash Kumar Bhaskar, Kausik Chakraborty, Laurent Counillon, Shantanu Sengupta, Mallorie Poët, Arjun Ray
This paper identifies phospholipids that regulate lipid transfer through CETP by enabling a novel 'gliding' mechanism, revealing their critical role in lipid movement and providing new therapeutic insights.
bioRxiv · Sep 4, 2025 · PreprintBiophysics