Sumoylation is largely dispensable for normal growth but facilitates heat tolerance in yeast
Marjan Moallem, Akhi Akhter, Giovanni L. Burke, John Babu, Benjamin G. Bergey, J. Bryan McNeil, Mohammad S. Baig, Emanuel Rosonina
This study shows that sumoylation is largely dispensable for normal yeast growth but essential for heat tolerance, as reduced Ubc9 activity leads to temperature sensitivity and transcriptional dysregulation.
Molecular and Cellular Biology · Jan 2, 2023Peer-reviewedMolecular Biology