NeuroscienceCommunications BiologyPeer-reviewed
Spike protein multiorgan tropism suppressed by antibodies targeting SARS-CoV-2
Molly Brady, Conor McQuaid, Alexander G. Solorzano…·Rashid Deane
This study uses fluorescently labeled spike protein to track its biodistribution in young mice, showing multiorgan uptake with liver accumulation and brain barrier protection, and finds anti-spike antibodies more effective than anti-ACE2 antibodies in reducing uptake.
13 citations