Author

Rashid Deane

University of Rochester MedicineORCID 0000-0002-0202-3551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Alexander G. SolorzanoiD· 2 shared Conor McQuaidiD· 2 shared Abigail Lepsch CombsiD· 1 shared Akib Rahman· 1 shared Angelique Johnson· 1 shared Chethana Venkatraman· 1 shared Hannah LeyvaiD· 1 shared Ian M. DickersoniD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Alexander G. SolorzanoORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 20, 2022

SARS-CoV-2 spike proteins uptake mediated by lipid raft ganglioside GM1 in human cerebrovascular cells

Conor McQuaid, Alexander G. Solorzano, Ian M. Dickerson, Rashid Deane

This study investigates SARS-CoV-2 spike protein uptake in human cerebrovascular cells, finding that ganglioside GM1 in lipid rafts mediates entry, independent of ACE2 in some cases.

2 citations

humanexperimental assay

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NeuroscienceCommunications BiologyPeer-reviewedNov 22, 2021

Spike protein multiorgan tropism suppressed by antibodies targeting SARS-CoV-2

Molly Brady, Conor McQuaid, Alexander G. Solorzano…·Rashid Deane

This study uses fluorescently labeled spike protein to track its biodistribution in young mice, showing multiorgan uptake with liver accumulation and brain barrier protection, and finds anti-spike antibodies more effective than anti-ACE2 antibodies in reducing uptake.

13 citations

mouseprotein structure

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