NeurosciencebioRxivPreprint
Pericyte Loss Reprogrammes Capillary Endothelium and Drives White Matter Injury in Small Vessel Disease
Dorota Stefancova, Audrey Chagnot, Michael D.E. Sewell…·Axel Montagne
1 citation
Author
Conor McQuaid
British Heart FoundationORCID 0000-0002-5163-8915Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- PathologybioRxivPreprint
Abrupt Pericyte Loss Precedes Endothelial Activation in Cerebral Small Vessel Disease
Audrey Chagnot, Daniela Jaime García, Conor McQuaid…·Axel Montagne
This study identifies pericyte loss preceding endothelial activation in cerebral small vessel disease through single-vessel analysis of human brain tissue.
3 citations - NeurosciencebioRxivPreprint
SARS-CoV-2 spike proteins uptake mediated by lipid raft ganglioside GM1 in human cerebrovascular cells
Conor McQuaid, Alexander G. Solorzano, Ian M. Dickerson, Rashid Deane
This study investigates SARS-CoV-2 spike protein uptake in human cerebrovascular cells, finding that ganglioside GM1 in lipid rafts mediates entry, independent of ACE2 in some cases.
2 citations - NeuroscienceCommunications BiologyPeer-reviewed
Spike protein multiorgan tropism suppressed by antibodies targeting SARS-CoV-2
Molly Brady, Conor McQuaid, Alexander G. Solorzano…·Rashid Deane
This study uses fluorescently labeled spike protein to track its biodistribution in young mice, showing multiorgan uptake with liver accumulation and brain barrier protection, and finds anti-spike antibodies more effective than anti-ACE2 antibodies in reducing uptake.
13 citations